Cellular Neurophysiology - J. Rettig

Our research is directed towards elucidating the molecular mechanisms underlying synaptic transmission. The ultimate goal is to understand how communication between nerve cells is mediated and modulated. Extrapolation of that knowledge from individual synapses to networks of the brain will enable us to understand the function of neural networks and identify potential strategies for treatment of CNS disorders. In order to achieve these goals we are using a combination of sophisticated electrophysiological and imaging methods on defined genetic model systems.